Alternating constipation and diarrhea: A more telling sign of colon cancer. Diarrhea: Caused by an overflow of intestinal fluid around a partial obstruction. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. The progression of colon cancer can often be recognized by the following additional symptoms: Constipation: Due in part to increasing bowel obstruction. Larger observational studies with multivariable analysis should be done to better describe the risk of colon cancer and HIV. In this study, HIV positive status was a risk factor for developing colon cancer at a younger age. When accounting for BMI, tobacco, and alcohol use, those with HIV were 10 years younger than those without HIV, 95% CI, 7.3-13 p < 0.001. Persons with both HIV and colon cancer were more likely to have a lower BMI (p-value < 0.001) and a history of smoking and alcohol use (p-value < 0.001), compared to patients with colon cancer only. ![]() ![]() The mean age of the colon cancer patient sample was 61.62 years for those without HIV and 51.31 years for those with HIV (p-value < 0.001). Among patients with both HIV and colon cancer, 78.95% (n = 90) were men and 21.05% (n = 24) were women (p-value < 0.001). Descriptive summaries were performed for gender, age, race/ethnicity, insurance status, tobacco/alcohol use, and BMI.Īmong patients with colon cancer only, 50.51% (n = 691) were men and 49.49% (n = 677) were women. HIV-infected women had an anal cancer rate of 30/100 000 person-years, and no cases were observed for HIV-noninfected women. In this cohort, 114 (7.7%) of the patients also had HIV. The unadjusted anal cancer incidence rates per 100,000 person-years were found to be 131 for HIV-infected MSM, 46 for other HIV-infected men, and 2 for HIV-noninfected men. Median patient age at colorectal cancer onset was 55. We retrospectively reviewed all patients (n = 1482) diagnosed with colon cancer between 20 at a large urban tertiary teaching hospital using ICD-9 and ICD-10 codes. Results: We included 184 colorectal cancer samples (38 HIV+, 146 HIV control). We sought to better characterize colon cancer among a predominantly Black cohort with and without HIV. ![]() Colon cancer is a leading cause of cancer-related morbidity and mortality in the USA.
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